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agt

AGT,即血管紧张素原,别名Angiotensinogen、ANHU、ANRT、AT-2。它是肾素-血管紧张素-醛固酮系统(RAAS)的关键组分,由AGT基因编码,在肝脏中合成。它通过肾素作用转化为血管紧张素I,再经血管紧张素转换酶(ACE)作用生成血管紧张素II,参与调节血压和体内电解质平衡。AGT的异常表达与高血压、子痫前期等疾病相关,其功能异常可能导致肾小管发育不良等病症。RNAi疗法ALN-AGT针对AGT,可能变革高血压治疗,通过减少给药频率提高患者依从性,具有重要的临床应用前景。

热销产品

Recombinant Human Angiotensinogen (AGT), partial (CSB-EP001463HU1)

验证数据

CSB-EP001463HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

AGT Recombinant Monoclonal Antibody (CSB-RA263831A0HU)

验证数据

CSB-RA263831A0HU

IHC image of CSB-RA263831A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human angiotensinogen (aGT) ELISA Kit (CSB-E08564h)

验证数据

CSB-E08564h 标准曲线

货号:CSB-E08564h

规格:96T/48T

灵敏度:19.5 pg/mL

检测范围:78 pg/mL-5000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

agt Antibodies

agt for Homo sapiens (Human)

agt Proteins

agt Proteins for Gallus gallus (Chicken)

agt Proteins for Mus musculus (Mouse)

agt Proteins for Ovis aries (Sheep)

agt Proteins for Homo sapiens (Human)

agt Proteins for Rattus norvegicus (Rat)

agt Proteins for Equus caballus (Horse)

agt Proteins for Bos taurus (Bovine)

agt Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

agt Proteins for Enterobacteria phage T4 (Bacteriophage T4)

agt Proteins for Pan troglodytes (Chimpanzee)

agt Proteins for Gorilla gorilla gorilla (Lowland gorilla)

agt Proteins for Callithrix jacchus (White-tufted-ear marmoset)

agt ELISA Kit

agt ELISA Kit for Homo sapiens (Human)

agt ELISA Kit for Mus musculus (Mouse)

agt ELISA Kit for Rattus norvegicus (Rat)