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AP3M1 Antibody

  • 中文名称：
    AP3M1兔多克隆抗体
  • 货号：
    CSB-PA001877GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y2T2
  • 基因名：
    AP3M1
  • 别名：
    Adapter-related protein complex 3 mu-1 subunit antibody; AP-3 adapter complex mu3A subunit antibody; AP-3 complex subunit mu-1 antibody; AP3M1 antibody; AP3M1_HUMAN antibody; Clathrin adaptor complex AP3 mu 3A subunit antibody; Mu-adaptin 3A antibody; mu3A antibody; Mu3A-adaptin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human AP3M1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
  • 基因功能参考文献：
    1. Structural basis for the recognition of tyrosine-based sorting signals by the mu3A subunit of the AP-3 adaptor complex PMID: 23404500
    2. results demonstrate that the intact and stable AP-3 complex is required for HIV-1 assembly and release, and the involvement of the AP-3 complex in late stages of the HIV-1 replication cycle is independent of clathrin-mediated endocytosis PMID: 22875976
    3. The present results suggest that AP3 complex genes might not play a major role in the pathogenesis of schizophrenia. PMID: 19481122
  • 亚细胞定位：
    Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Adaptor complexes medium subunit family
  • 数据库链接：

    HGNC: 569

    OMIM: 610366

    KEGG: hsa:26985

    STRING: 9606.ENSP00000347408

    UniGene: Hs.500104