OCIAD1 Antibody
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中文名称:OCIAD1兔多克隆抗体
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货号:CSB-PA016259GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:Q9NX40
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基因名:OCIAD1
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别名:Asrij antibody; FLJ20455 antibody; MGC111072 antibody; OCAD1_HUMAN antibody; OCIA antibody; OCIA domain containing 1 antibody; OCIA domain-containing protein 1 antibody; OCIAD1 antibody; Ovarian carcinoma immunoreactive antigen antibody; TPA018 antibody
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Human OCIAD1
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,WB,IHC,IF
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer.
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基因功能参考文献:
- Like OCIAD1, OCIAD2 is a cancer-related protein and its expression level increases during the course of malignant progression and is thought to be a very useful marker for evaluating the malignancy of ovarian mucinous tumors. PMID: 22726067
- OCIAD1 is a potential biomarker of thyroid carcinoma but had no significant additive effect on the risk of distant metastasis. PMID: 22081784
- This is the first study to indicate that OCIAD1 is a key player in generating ovarian cancer recurrence. PMID: 20515946
- Over-expressed in metastatic ovarian cancer. Effect of OCIAD1 on cell adhesion may be related to its function in ovarian cancer. Possibility of OCIAD1's role in tumor metastasis. PMID: 18328549
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亚细胞定位:Endosome.
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蛋白家族:OCIAD1 family
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组织特异性:Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.
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数据库链接:
HGNC: 16074
KEGG: hsa:54940
STRING: 9606.ENSP00000264312
UniGene: Hs.518750
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