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PMRT15 Antibody

  • 中文名称：
    PMRT15兔多克隆抗体
  • 货号：
    CSB-PA812747LA01DOA
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: PMRT15 antibody at 5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 44 kDa
      Observed band size: 44 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Arabidopsis thaliana PMRT15 Polyclonal antibody
  • Uniprot No.：
    Q8GWT4
  • 基因名：
    PMRT15
  • 别名：
    PMRT15 antibody; PMRT5 antibody; SKB1 antibody; At4g31120 antibody; F6E21.40Protein arginine N-methyltransferase 1.5 antibody; AtPMRT15 antibody; AtPMRT5 antibody; EC 2.1.1.319 antibody; Shk1 kinase-binding protein 1 homolog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Arabidopsis thaliana
  • 免疫原：
    Recombinant Arabidopsis thaliana Protein arginine N-methyltransferase 1.5 protein (513-637AA)
  • 免疫原种属：
    Arabidopsis thaliana
  • 标记方式：
    Non-conjugated

    本页面中的产品，PMRT15 Antibody (CSB-PA812747LA01DOA)，的标记方式是Non-conjugated。对于PMRT15 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA812747LB01DOA PMRT15 Antibody, HRP conjugated ELISA
    FITC CSB-PA812747LC01DOA PMRT15 Antibody, FITC conjugated
    Biotin CSB-PA812747LD01DOA PMRT15 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Methylates arginine residues of myelin basic protein (MBP) in vitro. Methylates symmetrically histone H4 of the FLC chromatin to form H4R3me2s, which in turn suppresses FLC expression to induce flowering. Regulates alternative splicing by methylating spliceosomal proteins. Involved in the post-transcriptional regulation of the circadian clock.
  • 基因功能参考文献：
    1. AtPRMT5 Regulates Shoot Regeneration through Mediating Histone H4R3 Dimethylation on KRPs and Pre-mRNA Splicing of RKP in Arabidopsis PMID: 27780782
    2. a new mechanism of plant root stem cell maintenance under DNA damage conditions that requires SKB1 PMID: 27090604
    3. Plants transduce stress-triggered NO signal to protein methylation machinery through S-nitrosylation of PRMT5 in response to environmental alterations. PMID: 28757206
    4. SKB1 and SKB1-mediated H4R3sme2 are required for the maintenance of SAM in Arabidopsis seedlings. PMID: 24349476
    5. A mutation in CAU1 significantly increased the expression level of the calcium signaling gene CAS, and functional disruption of CAS abolished the enhanced drought tolerance and stomatal [Ca(2+)]o signaling in cau1. PMID: 23943859
    6. SKB1 methylates the U6 snRNP LSM4 in response to salt stress and ABA. Loss of SKB1 influences pre-mRNA splicing. PMID: 21258002
    7. period lengthening associated with mutational disruption of prmt5 indicates that Rsme2 is a decoration important for the Arabidopsis clock PMID: 21097700
    8. key role for PRMT5 in the regulation of alternative splicing PMID: 20962777
    9. AtPRMT5 deficiency causes splicing defects in hundreds of genes involved in multiple biological processes. The splicing defects are identified in transcripts of several RNA processing factors involved in regulating flowering time. PMID: 20956294
    10. SKB1-mediated H4R3sme2 is a novel histone mark required for repression of FLC expression and flowering time control. PMID: 17363895
    11. involved in promotion of vegetative growth and FlOWERING LOCUS C-dependent flowering time regulation PMID: 17573539

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
  • 组织特异性：
    Highly expressed in flowers, roots and siliques, lower expression in stems and mature leaves (at protein level). Abundant in shoot apex, young leaves and leaf primordia, floral and inflorescence meristems, gynoecium, stamens, sepals and young siliques, bu
  • 数据库链接：

    KEGG: ath:AT4G31120

    STRING: 3702.AT4G31120.1

    UniGene: At.31771