消化系统疾病
消化系统疾病是一类影响消化道结构和功能的各种病症,包括食管、胃、小肠、大肠、肝脏、胆囊、胰腺等器官的疾病。这些疾病可能由多种因素引起,包括感染、自身免疫反应、遗传、生活方式和环境因素等。消化系统疾病的症状多样,从轻微的不适到严重的疼痛、出血或营养不良等。常见的消化系统疾病包括胃炎、消化性溃疡、胃癌、肝炎、肝硬化、胰腺炎、炎症性肠病等。
近年来,消化系统疾病的药物研发取得了显著进展。例如,针对消化性溃疡的治疗,新型药物如钾离子竞争性酸阻滞剂伏诺拉生(沃诺拉赞)已经上市,显示出良好的疗效和安全性。此外,针对胃食管反流病(GERD),新型抑酸药物的研发也在进行中,旨在提供更好的治疗效果和减少副作用。
在消化道肿瘤的治疗方面,免疫治疗和靶向治疗技术快速发展。例如,PD-1/PD-L1抗体和部分靶向治疗药物(如贝伐珠单抗和西妥昔单抗)已被批准用于晚期消化道肿瘤治疗。
消化系统疾病药物靶点
- AFP
- ALB
- AOC3
- CD247
- CD274
- CD276
- CD28
- CD40
- CD40LG
- CD44
- CD47
- CD86
- CDH17
- CEACAM5
- CEACAM6
- CFTR
- CLCA3P
- CLDN18
- CSF1R
- CSF2RA
- CSF3R
- CTLA4
- CXCL10
- CXCR4
- DLK1
- DLL4
- DNA2
- DRD4
- EGFR
- ENG
- EPCAM
- ERBB2
- ERBB3
- FGF19
- FGF21
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT1
- FOLR1
- FZD8
- GCGR
- GDF15
- GHR
- GIPR
- GLP1R
- GLP2R
- GPA33
- GPC3
- GUCY2C
- HAVCR2
- HGF
- IFNAR1
- IFNGR1
- IGF1R
- IL10RA
- IL12A
- IL12B
- IL12RB1
- IL13
- IL15
- IL15RA
- IL17A
- IL18
- IL1A
- IL1B
- IL1R1
- IL2
- IL22RA1
- IL23R
- IL2RA
- IL2RB
- IL2RG
- IL6
- IL7R
- INSR
- ITGA4
- ITGAV
- KDR
- KIT
- KLB
- KLRK1
- LAG3
- LILRB2
- MADCAM1
- MELTF
- MET
- MS4A1
- MSLN
- MUC1
- MUC16
- NECTIN4
- NT5E
- PDCD1
- PGF
- PSCA
- PTCRA
- SERPINA1
- TACSTD2
- TF
- TGFB1
- TIGIT
- TK
- TLR8
- TNF
- TNFRSF10B
- TNFRSF1A
- TNFRSF4
- TNFSF15
- TNFSF9
- TOP1
- TP53
- TPBG
- TYMS
- VEGFA
- VTCN1
- ZG16B
消化系统疾病靶点相关产品推荐
● 靶点蛋白
CSB-MP619964HU1
Measured by its binding ability in a functional ELISA. Immobilized PD-1 at 2 μg/ml can bind Anti-PD-1 recombinant antibody, the EC50 of human PD-1 protein is 6.087-7.854 ng/ml.
CSB-MP007763HU
Measured by its binding ability in a functional ELISA. Immobilized HER2 at 2 μg/ml can bind Trastuzumab, the EC50 is 2.179-2.825 ng/ml.
CSB-MP007479HU
Human EGF protein captured on COOH chip can bind Human EGFR protein, his and Myc tag (CSB-MP007479HU) with an affinity constant of 11.9nM as detected by LSPR Assay.
CSB-MP005498HU(A5)
Measured by its binding ability in a functional ELISA. Immobilized human CLDN18.2 (CSB-MP005498HU(A5)) at 5 μg/ml can bind anti-CLDN18.2 recombinant Monoclonal Antibody (CSB-RA005498A1HU), the the EC50 is 5.225-9.256 ng/ml.
CSB-MP878942HU1
Measured by its binding ability in a functional ELISA. Immobilized PD-L1 at 2 μg/ml can bind Anti- PD-L1 mouse monoclonal antibody(CSB-MA878942A1m, antigen from E.coli), the EC50 of human PD-L1 protein is 1.252-1.653 ng/mL
CSB-MP006163HU1
Measured by its binding ability in a functional ELISA. Immobilized CD152 at 2 μg/ml can bind Anti-CD152 rabbit monoclonal antibody (CSB-RA213310A0HU), the EC50 of human CD152 protein is 27.14-34.82 ng/ml.
CSB-MP009514HUb1
Measured by its binding ability in a functional ELISA. Immobilized Human GLP1R at 2 μg/mL can bind Anti-GLP1R recombinant antibody (CSB-RA009514MA1HU), the EC50 is 54.54-94.23 ng/mL.
CSB-MP023997HU1
Measured by its binding ability in a functional ELISA. Immobilized TNFSF9 at 2 μg/ml can bind TNFRSF9(CSB-MP023984HU1), the EC50 is 2.671-3.702 ng/mL
● 稳定细胞株
CT26/Human GPC3 Stable Cell Line
Untransfected CT26 cells (green line) and transfected Human GPC3 CT26 Stable cells (red line) were stained with anti-GPC3 antibody (CSB-RA009705A1HU) (2µg/1*106 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
HEK293T/Human CDH17 Stable Cell Line
Untransfected HEK293T cells (green line) and transfected Human CDH17 HEK293T stable cells (red line) were stained with anti-CDH17 antibody (CSB-RA613267MA1HU) (2µg/1*106 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
● 重组抗体
CSB-RA613267MA1HU
Untransfected HEK293T cells surface (green line) and transfected Human CDH17 HEK293T stable cells surface (red line) were stained with anti-CDH17 antibody (2µg/1*106 cells).
CSB-RA159341A0HU
Overlay histogram showing Jurkat cells stained with CSB-RA159341A0HU (red line) at 1:50.
CSB-RA215817A0HU
Overlay Peak curve showing MCF-7 cells stained with CSB-RA940669A0HU (red line) at 1:50.
CSB-RA215817A0HU
Overlay Peak curve showing PC3 cells surface stained with CSB-RA215817A0HU (red line) at 1:100.
产品名称 | 货号 | 靶点 | 反应种属 | 应用范围 |
---|---|---|---|---|
ALB Recombinant Monoclonal Antibody | CSB-RA264109A0HU | ALB | Human | ELISA, FC |
CD247 Recombinant Monoclonal Antibody | CSB-RA244537A0HU | CD247 | Human | ELISA, FC |
CD274 Recombinant Monoclonal Antibody | CSB-RA977797A0HU | CD274 | Human | ELISA, WB, IHC |
CD274 Recombinant Monoclonal Antibody | CSB-RA878942MA1HU | CD274 | Human | ELISA, IHC, FC |
CD40 Recombinant Monoclonal Antibody | CSB-RA004936MA1HU | CD40 | Human | ELISA, IF, FC |
CD44 Recombinant Monoclonal Antibody | CSB-RA004938A0HU | CD44 | Human | ELISA, WB, IHC |
CD44 Recombinant Monoclonal Antibody | CSB-RA292372A0HU | CD44 | Human | ELISA, WB, IHC, IF, FC |
CD44 Recombinant Monoclonal Antibody | CSB-RA004938MA1HU | CD44 | Human | ELISA, FC |
CD47 Recombinant Monoclonal Antibody | CSB-RA802124A0HU | CD47 | Human | ELISA, WB, IHC, IF |
CD86 Recombinant Monoclonal Antibody | CSB-RA004965A0HU | CD86 | Human | ELISA, WB |
CDH17 Recombinant Monoclonal Antibody | CSB-RA613267MA1HU | CDH17 | Human | ELISA,FC |
CEACAM5 Recombinant Monoclonal Antibody | CSB-RA005165MA3HU | CEACAM5 | Human | ELISA, IF, FC |
CEACAM5 Recombinant Monoclonal Antibody | CSB-RA005165MA1HU | CEACAM5 | Human | ELISA |
CLDN18 Recombinant Monoclonal Antibody | CSB-RA005498A2HU | CLDN18 | Human | ELISA, FC |
Claudin-18.2 Recombinant Monoclonal Antibody | CSB-RA005498A1HU | CLDN18 | Human | ELISA, FC |
CTLA4 Recombinant Monoclonal Antibody | CSB-RA213310A0HU | CTLA4 | Human | ELISA, IHC |
CTLA4 Recombinant Monoclonal Antibody | CSB-RA006163MA1HU | CTLA4 | Human, Mouse | ELISA, WB, IF, FC |
CXCL10 Recombinant Monoclonal Antibody | CSB-RA903061A0HU | CXCL10 | Human | ELISA, IHC |
CXCR4 Recombinant Monoclonal Antibody | CSB-RA569311A0HU | CXCR4 | Human | ELISA, IF |
CXCR4 Recombinant Monoclonal Antibody | CSB-RA006254MA01HU | CXCR4 | Human | ELISA |
● ELISA试剂盒
产品名称 | 货号 | 靶点 | 检测范围 | 灵敏度 |
---|---|---|---|---|
Human Alpha-fetoprotein,AFP ELISA Kit | CSB-E04770h | AFP | 1.563 ng/mL-100 ng/mL | 1.332 ng/mL |
Mouse Alpha-fetoprotein,AFP ELISA Kit | CSB-E08282m | AFP | 1.23 ng/ml-900 ng/ml. | 1.23 ng/ml. |
Rat Alpha-fetoprotein,AFP ELISA Kit | CSB-E08281r | AFP | 15.6 pg/mL-1000 pg/mL | 3.9 pg/mL |
Pig Alpha-fetoprotein(AFP) ELISA kit | CSB-EL001421PI | AFP | 3.12 ng/mL-200 ng/mL | 0.78 ng/mL |
Bovine Albumin(Alb) ELISA kit | CSB-E08664b | ALB | 0.313 μg/mL-80 μg/mL | 0.148 μg/mL |
Mouse Albumin (Alb)ELISA Kit | CSB-E13878m | ALB | 0.781 μg/mL-200 μg/mL | 0.110 μg/mL |
Dog Albumin(Alb) ELISA Kit | CSB-E15757c | ALB | 0.273 μg/mL-35 μg/mL | 0.266 μg/mL |
Sheep Albumin (Alb)ELISA Kit | CSB-E15839Sh | ALB | 350 μg/mL-21.88 μg/mL | 5.5 μg/mL |
Horse Albumin(Alb) ELISA Kit | CSB-E16205Hs | ALB | 1.25 μg/mL-80 μg/mL | 1.247 μg/mL |
Pig Albumin (Alb) ELISA Kit | CSB-E16207p | ALB | 0.03 μg/mL-7000 μg/mL | 0.03 μg/mL |
Goat Albumin (Alb)ELISA Kit | CSB-E15758G | ALB | 0.17 μg/mL-350 μg/mL | 0.17 μg/mL |
Guinea Pig Albumin(Alb) ELISA kit | CSB-E15765Gp | ALB | 0.156 μg/mL-10 μg/mL | 0.09 μg/mL |
Rabbit Albumin(Alb) ELISA Kit | CSB-E16204Rb | ALB | 0.273 μg/mL-70 μg/mL | 0.117 μg/mL |
Mouse Membrane primary amine oxidase(AOC3) ELISA kit | CSB-EL001855MO | AOC3 | 1.25 ng/mL-80 ng/mL | 0.31 ng/mL |
Rat Membrane primary amine oxidase(AOC3) ELISA kit | CSB-EL001855RA | AOC3 | 7.8 ng/mL-500 ng/mL | 1.95 ng/mL |
Human T-cell surface glycoprotein CD3 zeta chain (CD247) ELISA kit | CSB-EL004904HU | CD247 | 0.156 ng/mL-10 ng/mL | 0.039 ng/mL |
Human Programmed Death Ligand-1(PD-L1/CD274) ELISA Kit | CSB-E13644h | CD274 | 15.6 pg/mL-1000 pg/mL | 3.9 pg/mL |
Mouse Programmed cell death 1 ligand 1(CD274) ELISA kit | CSB-EL004911MO | CD274 | 31.25 pg/mL-2000 pg/mL | 7.81 pg/mL |
Human Soluble CD276,sCD276/sB7-H3 ELISA Kit | CSB-E14285h | CD276 | 3.12 ng/mL-200 ng/mL | 0.78 ng/mL |
Human soluble cluster of differentiation 28,sCD28 ELISA Kit | CSB-E09296h | CD28 | 0.625 ng/mL-40 ng/mL | 0.156 ng/mL |