Your Good Partner in Biology Research

呼吸道疾病

呼吸道疾病是涉及从鼻腔到肺部的呼吸系统的多种疾病群。常见的类型包括感冒和流感(由病毒引起)、支气管炎(支气管的炎症)、哮喘(慢性炎症性肺病)、慢性阻塞性肺病(COPD,包括慢性支气管炎和肺气肿)、肺炎(肺部感染)、肺结核(由结核杆菌引起的传染性疾病)以及肺癌(肺部恶性肿瘤)。这些疾病可能由病毒、细菌、过敏原、污染物、吸烟和其他环境因素引起。

目前,针对呼吸道疾病的药物开发主要集中在以下几个方面:

  • 炎症介质:即抗炎药物,目的是减少哮喘和COPD等炎症性肺病的症状。同时,针对特定炎症介质的生物制剂正在开发,如抗IL-5和抗IL-13,用于治疗严重的哮喘。
  • 抗菌药物:针对耐药性细菌的新型抗菌药物对于治疗肺炎等呼吸道感染至关重要。
  • 免疫检查点:如PD-1/PD-L1抑制剂等免疫疗法,用于治疗肺癌。
  • 基因治疗:针对遗传性呼吸系统疾病,如囊性纤维化的基因治疗正在研究中。
  • 肿瘤标志物:靶向治疗,如EGFR抑制剂,正在非小细胞肺癌的治疗中发挥作用。
  • 疫苗:流感疫苗和肺炎球菌疫苗等针对呼吸道疾病的疫苗不断更新以适应病原体的变异。

呼吸道疾病靶点相关产品推荐

● 靶点蛋白

CSB-MP619964HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized PD-1 at 2 μg/ml can bind Anti-PD-1 recombinant antibody, the EC50 of human PD-1 protein is 6.087-7.854 ng/ml.

CSB-MP878942HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized PD-L1 at 2 μg/ml can bind Anti- PD-L1 mouse monoclonal antibody (CSB-MA878942A1m, antigen from E.coli), the EC50 of human PD-L1 protein is 1.252-1.653 ng/mL

CSB-MP007479HU Activity Verified

Human EGF protein captured on COOH chip can bind Human EGFR protein, his and Myc tag (CSB-MP007479HU) with an affinity constant of 11.9nM as detected by LSPR Assay.

CSB-MP866317HU Activity Verified

SARS-CoV-2 Spike protein RBD his/sumostar tag (CSB-YP3324GMY1) captured on COOH chip can bind Human ACE2 protein Fc tag (CSB-MP866317HU) with an affinity constant of 100 nM as detected by LSPR Assay.

TACSTD2(TROP2)
CSB-MP023072HU1
CSB-MP023072HU1 Activity Verified

Measured in cell activity assay using U937 cells, the EC50 for this effect is 190.2-298.6 ng/ml.

CSB-MP006163HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized CD152 at 2 μg/ml can bind Anti-CD152 rabbit monoclonal antibody (CSB-RA213310A0HU), the EC50 of human CD152 protein is 27.14-34.82 ng/ml.

CSB-MP011661HU2-B Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized Human IL4 (CSB-MP011659HU) at 2μg/mL can bind biotinylated Human IL4R,the EC50 is 12.68-14.23 ng/mL.

CSB-MP007763HU Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized HER2 at 2 μg/ml can bind Trastuzumab, the EC50 is 2.179-2.825 ng/ml.

产品名称 货号 靶点 来源 蛋白标签
Recombinant Human Angiotensin-converting enzyme 2 (ACE2), partial (Active) CSB-AP005671HU ACE2 Mammalian cell C-terminal 6xHis-tagged
Recombinant Human Angiotensin-converting enzyme 2 (ACE2), partial, Biotinylated (Active) CSB-MP866317HU-B ACE2 Mammalian cell C-terminal mFc-Avi-tagged
Recombinant Human Angiotensin-converting enzyme 2 (ACE2), partial (Active) CSB-MP866317HU ACE2 Mammalian cell C-terminal hFc-tagged
Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active) CSB-MP3414MOV ACE2 Mammalian cell C-terminal hFc-tagged
Recombinant Paguma larvata Angiotensin-converting enzyme 2 (ACE2), partial (Active) CSB-MP684964PAL ACE2 Mammalian cell C-terminal hFc-tagged
Recombinant Human Basigin (BSG), partial (Active) CSB-MP002831HU1 BSG Mammalian cell C-terminal hFc-tagged
Recombinant Human Programmed cell death 1 ligand 1 (CD274), partial (Active) CSB-MP878942HU1 CD274 Mammalian cell C-terminal hFc-tagged
Recombinant Human CD276 antigen (CD276), partial (Active) CSB-MP733578HU CD276 Mammalian cell C-terminal hFc-Myc-tagged
Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active) CSB-AP005181HU CD40 Mammalian cell C-terminal Fc-tagged
Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active) CSB-MP004936HU1 CD40 Mammalian cell C-terminal hFc-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) CSB-AP005201HU CD47 Mammalian cell C-terminal 6xHis-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) CSB-AP005211HU CD47 Mammalian cell C-terminal Fc-tagged
Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) CSB-MP004940HU CD47 Mammalian cell C-terminal hFc-tagged
Recombinant Human T-lymphocyte activation antigen CD86 (CD86), partial (Active) CSB-AP005161HU CD86 Mammalian cell C-terminal 6xHis-tagged
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) (E398K) (Active) CSB-MP005165HU CEACAM5 Mammalian cell C-terminal 10xHis-tagged
Recombinant Human Claudin-6 (CLDN6)-VLPs (Active) CSB-MP005508HU(A4) CLDN6 Mammalian cell C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions)
Recombinant Human Claudin-6 (CLDN6)-VLPs, Fluorescent (Active) CSB-MP005508HU(A4)f4 CLDN6 Mammalian cell C-terminal GFP-tagged (This tag can be tested only under denaturing conditions)
Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) (Active) CSB-AP003581HU CSF2 E.coli Tag-Free
Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) (Active) CSB-AP003601HU CSF2 Mammalian cell C-terminal 6xHis-tagged
Recombinant Mouse Granulocyte-macrophage colony-stimulating factor (Csf2) (Active) CSB-AP003651MO Csf2 Mammalian cell C-terminal 6xHis-tagged

● 稳定细胞株

CSB-SC005508HU FACS

HEK293T/Human CLDN6 Stable Cell Line

CSB-SC007681HU

Untransfected HEK293T cells (green line) and transfected Human CLDN6 HEK293T stable cells (red line) were stained with anti-CLDN6/9 antibody (CSB-RA005508MA1HU) (2µg/1*106 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

CSB-SC020067HU FACS

CT26/Human ROR1 Stable Cell Line

CSB-SC020067HU

Untransfected CT26 cells (green line) and transfected Human ROR1 CT26 stable cells (red line) were stained with anti-ROR1 antibody (CSB-RA020067A1HU) (2µg/1*106 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

CSB-SC882142HU FACS

HEK293F/Human DLL3 Stable Cell Line

CSB-SC007681HU

Untransfected HEK293 cells (green line) and transfected Human DLL3 HEK293 stable cells (red line) were stained with anti-DLL3 antibody (rovalpituzumab-like) (2µg/1*106 cells), washed and then followed by FITC-conjugated anti-Human IgG1 Fc antibody and analyzed with flow cytometry.

● 重组抗体

CD274 Recombinant Monoclonal Antibody
CSB-RA878942MA1HU
CSB-RA878942MA1HU FC

Overlay Peak curve showing Hela cells surface stained with CSB-RA878942MA1HU (red line) at 1:100.

EGFR Recombinant Monoclonal Antibody
CSB-RA159341A0HU
CSB-RA159341A0HU FC

Overlay histogram showing Jurkat cells stained with CSB-RA159341A0HU (red line) at 1:50.

CD247 Recombinant Monoclonal Antibody
CSB-RA244537A0HU
CSB-RA244537A0HU FC

Overlay Peak curve showing Jurkat cells surface stained with CSB-RA244537A0HU (red line) at 1:50.

CTLA4 Recombinant Monoclonal Antibody
CSB-RA006163MA1HU
CSB-RA006163MA1HU FC

Overlay Peak curve showing JK cells surface stained with CSB-RA006163MA1HU (red line) at 1:50.

产品名称 货号 靶点 反应种属 应用范围
ALB Recombinant Monoclonal Antibody CSB-RA264109A0HU ALB Human ELISA, FC
CD247 Recombinant Monoclonal Antibody CSB-RA244537A0HU CD247 Human ELISA, FC
CD27 Recombinant Monoclonal Antibody CSB-RA953976A0HU CD27 Human ELISA, WB
CD274 Recombinant Monoclonal Antibody CSB-RA977797A0HU CD274 Human ELISA, WB, IHC
CD274 Recombinant Monoclonal Antibody CSB-RA878942MA1HU CD274 Human ELISA, IHC, FC
CD4 Recombinant Monoclonal Antibody CSB-RA004935A0HU CD4 Human ELISA, WB, IHC
CD40 Recombinant Monoclonal Antibody CSB-RA004936MA1HU CD40 Human ELISA, IF, FC
CD47 Recombinant Monoclonal Antibody CSB-RA802124A0HU CD47 Human ELISA, WB, IHC, IF
CD86 Recombinant Monoclonal Antibody CSB-RA004965A0HU CD86 Human ELISA, WB
CEACAM5 Recombinant Monoclonal Antibody CSB-RA005165MA3HU CEACAM5 Human ELISA, IF, FC
CEACAM5 Recombinant Monoclonal Antibody CSB-RA005165MA1HU CEACAM5 Human ELISA
CTLA4 Recombinant Monoclonal Antibody CSB-RA213310A0HU CTLA4 Human ELISA, IHC
CTLA4 Recombinant Monoclonal Antibody CSB-RA006163MA1HU CTLA4 Human, Mouse ELISA, WB, IF, FC
DLL3 Recombinant Monoclonal Antibody CSB-RA882142A1HU DLL3 Human ELISA, FC
Phospho-EGFR (Y1092) Recombinant Monoclonal Antibody CSB-RA007479A1092phHU EGFR Human ELISA, WB
Phospho-EGFR (Y1068) Recombinant Monoclonal Antibody CSB-RA007479A1068phHU EGFR Human ELISA, WB
EGFR Recombinant Monoclonal Antibody CSB-RA159341A0HU EGFR Human ELISA, WB, IHC, IF, FC
EGFR Recombinant Monoclonal Antibody CSB-RA794061A0HU EGFR Human ELISA, WB, IHC
EGFR Recombinant Monoclonal Antibody CSB-RA159341MA1HU EGFR Human ELISA, IHC, FC
ELANE Recombinant Monoclonal Antibody CSB-RA200985A0HU ELANE Human ELISA, IHC, FC

● ELISA试剂盒

产品名称 货号 靶点 检测范围 灵敏度
Rat Angiotensin converting enzyme 2, ACE2 ELISA Kit CSB-E14308r ACE2 0.02 ng/ml - 20 ng/ml 0.02 ng/ml
Human Angiotensin converting enzyme 2, ACE2 ELISA Kit CSB-E04489h ACE2 0.156 ng/mL-10 ng/mL 0.039 ng/mL
Mouse Angiotensin converting enzyme 2(ACE2)ELISA Kit CSB-E17204m ACE2 6.25 pg/mL-400 pg/mL 1.56 pg/mL
Bovine Albumin(Alb) ELISA kit CSB-E08664b ALB 0.313 μg/mL-80 μg/mL 0.148 μg/mL
Mouse Albumin (Alb)ELISA Kit CSB-E13878m ALB 0.781 μg/mL-200 μg/mL 0.110 μg/mL
Dog Albumin(Alb) ELISA Kit CSB-E15757c ALB 0.273 μg/mL-35 μg/mL 0.266 μg/mL
Sheep Albumin (Alb)ELISA Kit CSB-E15839Sh ALB 350 μg/mL-21.88 μg/mL 5.5 μg/mL
Horse Albumin(Alb) ELISA Kit CSB-E16205Hs ALB 1.25 μg/mL-80 μg/mL 1.247 μg/mL
Pig Albumin (Alb) ELISA Kit CSB-E16207p ALB 0.03 μg/mL-7000 μg/mL 0.03 μg/mL
Goat Albumin (Alb)ELISA Kit CSB-E15758G ALB 0.17 μg/mL-350 μg/mL 0.17 μg/mL
Guinea Pig Albumin(Alb) ELISA kit CSB-E15765Gp ALB 0.156 μg/mL-10 μg/mL 0.09 μg/mL
Rabbit Albumin(Alb) ELISA Kit CSB-E16204Rb ALB 0.273 μg/mL-70 μg/mL 0.117 μg/mL
Bovine Angiopoietin-1(ANGPT1) ELISA kit CSB-EL001706BO ANGPT1 12.5 ng/mL-800 ng/mL 1.384 ng/mL
Human Angiopoietin-1(ANGPT1) ELISA kit CSB-EL001706HU ANGPT1 1.25 ng/mL-80 ng/mL 0.091 ng/mL
Mouse Angiopoietin 1,ANG-1 ELISA Kit CSB-E07302m ANGPT1 1.25 ng/mL-80 ng/mL 0.312 ng/mL
Rat Angiopoietin 1,ANG-1 ELISA Kit CSB-E07303r ANGPT1 6.25 ng/mL-400 ng/mL 1.56 ng/mL
Pig Angiopoietin 1,ANG-1 ELISA Kit CSB-E08457p ANGPT1 6 ng/mL-200 ng/mL 6 ng/mL
Human Tyrosine-protein kinase receptor UFO (AXL) ELISA Kit CSB-EL002476HU AXL 31.25 pg/mL-2000 pg/mL 7.81 pg/mL
Mouse Tyrosine-protein kinase receptor UFO(AXL) ELISA Kit CSB-EL002476MO AXL 31.25 pg/ml-2000 pg/ml 7.81 pg/ml
Human Cluster of differentiation 147,CD147 Elisa Kit CSB-E12994h BSG 12.5 pg/mL-800 pg/mL 3.12 pg/mL